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Unmet needs in bipolar depression
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Unmet needs in bipolar depression

Author: Mark A Frye Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California; Michael J Gitlin Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California; Lori L Altshuler Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California
Edition/Format: Article Article : English
Publication:Depression and Anxiety, v19 n4 (2004): 199-208
Other Databases: WorldCatWorldCat
Summary:
Bipolar disorders, particularly bipolar spectrum disorders, frequently go unrecognized and undiagnosed by clinicians and thus remain untreated or inappropriately treated. Although the symptoms of bipolar I disorder are widely acknowledged and recognized among clinicians, epidemiology sampling studies over the past several years have found that bipolar II disorder and bipolar spectrum disorders are likely to be more  Read more...
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Document Type: Article
All Authors / Contributors: Mark A Frye Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California; Michael J Gitlin Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California; Lori L Altshuler Affiliation: University of California, Los Angeles, School of Medicine, Los Angeles, California
ISSN:1091-4269
Language Note: English
Unique Identifier: 5156012205
Notes: Number of Tables: 1
Number of References: 78
Awards:

Abstract:

Bipolar disorders, particularly bipolar spectrum disorders, frequently go unrecognized and undiagnosed by clinicians and thus remain untreated or inappropriately treated. Although the symptoms of bipolar I disorder are widely acknowledged and recognized among clinicians, epidemiology sampling studies over the past several years have found that bipolar II disorder and bipolar spectrum disorders are likely to be more prevalent and more challenging to diagnose, particularly as depressive presentations are far more common in these groups. Bipolar disorder is associated with increased morbidity and mortality, as well as higher healthcare costs, but it is unclear how much of the consequences of bipolar disorder are unrecognized in the face of poor recognition of bipolar II and bipolar spectrum disorders. This article addresses challenges in diagnosing and treating bipolar disorder in the face of a depressive episode, and offers guidelines for recognizing and appropriately managing these patients. Studies with the newer anticonvulsant mood stabilizer lamotrigine have shown antidepressant effects in bipolar disorder, and may fill an unmet need for treatment options in patients who present with depression in the context of bipolar disorder. Depression and Anxiety 19:199-208, 2004. © 2004 Wiley-Liss, Inc.

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