Microbial transformation of artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger. (Article, 2006) [WorldCat.org]
skip to content
Microbial transformation of artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger.
ClosePreview this item
Checking...

Microbial transformation of artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger.

Author: IA Parshikov Affiliation: Department of Medicinal Chemistry, University of Mississippi, University, MS 38677, USA.; B Miriyala; KM Muraleedharan; MA Avery; JS Williamson
Edition/Format: Article Article : English
Publication:Journal of industrial microbiology & biotechnology, 2006 May; 33(5): 349-52
Other Databases: WorldCat
Summary:
Transformation of the anti-malarial drug artemisinin by the fungi Eurotium amstelodami and Aspergillus niger were investigated. Cultures were grown in sucrose/malt broth with artemisinin for 14 days and extracted with ethyl acetate. Extracts were characterized by liquid chromatography. Two metabolites from each fungal extract were isolated and identified using mass spectrometry and nuclear magnetic resonance.  Read more...
Rating:

based on 1 rating(s) 1 with a review

More like this
&AllPage.SpinnerRetrieving;

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Document Type: Article
All Authors / Contributors: IA Parshikov Affiliation: Department of Medicinal Chemistry, University of Mississippi, University, MS 38677, USA.; B Miriyala; KM Muraleedharan; MA Avery; JS Williamson
ISSN:1367-5435
Language Note: English
Unique Identifier: 110513377
Awards:

Abstract:

Transformation of the anti-malarial drug artemisinin by the fungi Eurotium amstelodami and Aspergillus niger were investigated. Cultures were grown in sucrose/malt broth with artemisinin for 14 days and extracted with ethyl acetate. Extracts were characterized by liquid chromatography. Two metabolites from each fungal extract were isolated and identified using mass spectrometry and nuclear magnetic resonance. 5Beta-hydroxyartemisinin and 7beta-hydroxyartemisinin were isolated in 63 and 32% yields, respectively, from the extract of E. amstelodami, and 80 and 19%, respectively, from the extract of A. niger.

Reviews

User-contributed reviews

WorldCat User Reviews (1)

You can found more in book of Igor A. Parshikov ISBN 978-1-68419-775-0

by igorcen (WorldCat user published 2016-07-19) Excellent Permalink

You can found more in book:

Igor A. Parshikov. Microorganisms in Chemistry of Terpenoids. – Dallas: Primedia E-launch LLC, 2016. − 102 p. IBSN 978-1-68419-775-0

Links:

http://www.bookwire.com/book/USA/Microorganisms-in-Chemistry-of-Terpenoids-9781684197750-Parshikov-Igor-A-56140330

https://openlibrary.org/people/igorcen/lists/OL99679L/Back_in_Science

 

...
Read more...  Read more...
  • Was this review helpful to you?
  •   
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

All user tags (7)

View most popular tags as: tag list | tag cloud

Similar Items

User lists with this item (2)

Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.